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May 16, 2008 |
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Faculty
CHARLES F. STEVENS
TEL: 858-453-4100, Ext. 1155
FAX: 858-450-2172
email: cfs@salk.edu
M.D., Yale University
Ph.D., Rockefeller University
Adjunct Professor of Pharmacology
Key Words: Synaptic Transmission; Receptors; Memory
The work in my laboratory centers on mechanisms responsible for synaptic transmission. These problems are approached by a combination of molecular, biological, electrophysiological, anatomical and theoretical methods. We study neurons both in dissociated cell culture and in brain slices, and we also investigate the function of individual membrane proteins of importance for synaptic transmission that have been expressed in neurons or other cell types. One main area of current work deals with the function of hippocampal synapses, and especially with mechanisms of synaptic plasticity and the relevance of plasticity to neuronal computations.
SELECTED PUBLICATIONS:
Dobrunz, L.E. and Stevens, C.F. (1999). Response of hippocampal synapses to natural stimulation patterns. Neuron 22: 157-166.
Murthy, V.N. and Stevens, C.F. (1999). Reversal of synaptic vesicle docking at central synapses. Nature Neuroscience 2:503-507.
Stevens, C.F. and Williams, J.H. (2000). "Kiss and run" exocytosis at hippocampal synapses. PNAS 97:12828-12833.
Schikorski, T.
and Stevens, C.F. (2001). Morphological correlates of functionally defined
synaptic vesicle populations. Nature Neuroscience 4:391-395.
Adams, Joseph A. Akassoglou, Katerina Bourne, Philip E. Brown, Joan Heller Brunton, Laurence L. Dennis, Edward A. Dixon, Jack E. Evans, Sylvia Feramisco, James R. Guan, Kun-Liang Hook, Vivian Insel, Paul A. Karin, Michael Leffert, Hyam L. McCammon, J. Andrew Newton, Alexandra C. Printz, Morton P. Taylor, Palmer Taylor, Susan Tsien, Roger Y. Tukey, Robert H. Yaksh, Tony L. Yang, Jing Khan, Imran M. Seasholtz, Tammy M. Williams, David S. Abraham, Robert T. Bartfai, Tamas Bonneville, Anne K. Chun, Jerold J. M. Crooke, Stanley T. Cuatrecasas, Pedro Evans, Ronald M. Stevens, Charles F. TenEyck, Lynn F. Vallon, Volker Venter, J. Craig Verkhivker, Gennady Wooley, John C.
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