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Research Focus Areas:

> Signal Transduction

> Computational Biology and Drug Design

> Integrated System and Animal Models

> Pharmacogenomics

> Superfund Basic Research Program

macrophage

Feature:
Aspirin, Take Two
White blood cell research shows how causing and conquering inflammation are inextricably linked


In a new paper, published this week in the online early edition of PNAS, researchers at the University of California, San Diego School of Medicine conclude that aspirin has a second effect: Not only does it kill cyclooxygenase, thus preventing production of the prostaglandins that cause inflammation and pain, it also prompts the enzyme to generate another compound that hastens the end of inflammation, returning the affected cells to homeostatic health.

“Aspirin causes the cyclooxygenase to make a small amount of a related product called 15-HETE,” said senior author Edward A. Dennis, PhD, Distinguished Professor of Pharmacology, Chemistry and Biochemistry. “During infection and inflammation, the 15-HETE can be converted by a second enzyme into lipoxin, which is known to help reverse inflammation and cause its resolution – a good thing.”
Read more...


Comming Soon!
> 2014-2015 Seminar Schedule
> 2014-2015 Research Discussions


Seminars:

Tuesday, September 9, 2014
Dr. Vladlen Slepak
University of Miami School of Medicine
The Role of Gbeta5-RGS7 Complex in Signaling and Hormone Secretion
12:00 pm, Leichtag, Room 107

Host: JoAnn Trejo

Tuesday, September 16, 2014
Dr. Daniel Kelly
Sanford-Burnham (FL)
Cardiac energy metabolic switches as therapeutic targets
12:00 pm, Leichtag, Room 107
Host: Mohit Jain

Tuesday, September 30, 2014
Dr. Hugh Rosen
The Scripps Research Institute
TBD
12:00 pm, Leichtag, Room 107
Host: Paul Insel

Tuesday, September 30, 2014
Dr. Emmanuel Mignot
Stanford
TBD
12:00 pm, Leichtag, Room 107
Host: William Joiner

Tuesday, November 18, 2014
Dr. Andrey Shaw
Washington University School of Medicine
TBD
12:00 pm, Leichtag, Room 107
Host: Susan Taylor

> 2013-2014 Seminar Schedule
> 2012-2013 Seminar Schedule
> 2011-2012 Seminar Schedule
> 2010-2011 Seminar Schedule
> 2009-2010 Seminar Schedule
> 2008-2009 Seminar Schedule





 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Department News:

July 1, 2014
Jack Dixon
has been selected as the recipient of the ASBMB - The Earl and Thressa Stadtman Distinguished Scientist Award
Congratulations, Jack!

June 30, 2014
JoAnn Trejo has been selected as the recipient of the ASBMB Ruth Kirschstein Diversity in Science Award. Congratulations, JoAnn!

June 4, 2014
Congratulations to the Pharmacology Department Retreat Poster Winners.:

Best Graduate Student Posters
Corina Antal - Newton Lab
Lindy Jiang - Yang Lab
Bailey Miller - Gerwick/Hook Lab

Best Postdoc Posters
Michael Dores - Trejo Lab
Clare Puddifoot - Joiner Lab

May 1, 2014
Our former graduate student, Ryan Hibbs, is one of six winners of the McKnight Scholar Award for 2014, a very prestigious award for young neuroscientists.

April 4, 2014
Nora Laiken
is selected as recipient of the 2013 – 2014 Distinguished Teaching Award for Non-Senate Members. Congratulations, Nora!

July 26, 2013
Palmer Taylor
has been Awarded France's Legion of Honour Award

March 22, 2013
Susan Taylor has been awarded the Biochemical Society 2014 Centenary Award. The Biochemical Society, based in London, recognizes scientists for excellence and the profound implications that their work has for the research community and wider society.

December 14, 2012
Holiday Party Karaoke!

Yakkety Yak
Sweet Caroline
Crazy


> News Archives

 

 

 

 

 


 
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