Research Focus Areas:

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> Pharmacogenomics

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Aspirin, Take Two
White blood cell research shows how causing and conquering inflammation are inextricably linked

In a new paper, published this week in the online early edition of PNAS, researchers at the University of California, San Diego School of Medicine conclude that aspirin has a second effect: Not only does it kill cyclooxygenase, thus preventing production of the prostaglandins that cause inflammation and pain, it also prompts the enzyme to generate another compound that hastens the end of inflammation, returning the affected cells to homeostatic health.

“Aspirin causes the cyclooxygenase to make a small amount of a related product called 15-HETE,” said senior author Edward A. Dennis, PhD, Distinguished Professor of Pharmacology, Chemistry and Biochemistry. “During infection and inflammation, the 15-HETE can be converted by a second enzyme into lipoxin, which is known to help reverse inflammation and cause its resolution – a good thing.”

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Department News:

July 1, 2014
Jack Dixon
has been selected as the recipient of the ASBMB - The Earl and Thressa Stadtman Distinguished Scientist Award
Congratulations, Jack!

June 30, 2014
JoAnn Trejo has been selected as the recipient of the ASBMB Ruth Kirschstein Diversity in Science Award. Congratulations, JoAnn!

June 4, 2014
Congratulations to the Pharmacology Department Retreat Poster Winners.:

Best Graduate Student Posters
Corina Antal - Newton Lab
Lindy Jiang - Yang Lab
Bailey Miller - Gerwick/Hook Lab

Best Postdoc Posters
Michael Dores - Trejo Lab
Clare Puddifoot - Joiner Lab

May 1, 2014
Our former graduate student, Ryan Hibbs, is one of six winners of the McKnight Scholar Award for 2014, a very prestigious award for young neuroscientists.

April 4, 2014
Nora Laiken
is selected as recipient of the 2013 – 2014 Distinguished Teaching Award for Non-Senate Members. Congratulations, Nora!

July 26, 2013
Palmer Taylor
has been Awarded France's Legion of Honour Award

March 22, 2013
Susan Taylor has been awarded the Biochemical Society 2014 Centenary Award. The Biochemical Society, based in London, recognizes scientists for excellence and the profound implications that their work has for the research community and wider society.

December 14, 2012
Holiday Party Karaoke!

Yakkety Yak
Sweet Caroline

September 21, 2012
Pharmacology Thesis Award Winners Announced:
Mark Eckert (Yang Lab)
Noel Warfel (Newton Lab)

Congratulations to two terrific students and their most capable mentors!

April 23, 2012
Jack Dixon named Royal Society Fellow

December 13, 2011
Alexandra Newton named AAAS Fellow

November 21, 2011
A Call to Congress to Protect Science Funding:

October 24, 2011
Michael Karin In Atlantic

October 17, 2011
Michael Karin elected as new member of Institute of Medicine of the National Academy of Sciences

May 26, 2011
Congratulations to the following Poster Winners at the Pharmacology Retreat!
Loren Brown
Graduate Student, Insel Lab
Meghan Miller
Graduate Student, P. Taylor Lab
Sunny Yang Xiang
Postdoc, Heller Brown Lab
David Lu
Graduate Student, Insel Lab
Karen Tumaneng
Graduate Student, Guan Lab

May 4, 2011
J. Andrew McCammon elected into the National Academy of Sciences

March 14, 2011
Research from the group of Jing Yang provides a new twist on tumor metastasis inCancer Cell

Funding Fest 2011 starts May 5th!

April 5, 2011
Roger Tsien Modifies plant protein to provide a way to see the previously unseen in Public Library of Science (PLoS).


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