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Signaling and Molecular Pharmacology Program

The Signaling and Molecular Pharmacology program is focused on understanding the molecular and cellular mechanisms of how cells transduce information, and how these mechanisms are deregulated in disease. Specifically, research is directed at understanding signaling from initial ligand binding to cellular receptors and propagation by signaling cascades in the cell to culmination in a cellular response. Novel imaging techniques are used to visualize intracellular signaling in real time in live cells, and biochemical, molecular biological, cellular and biophysical approaches are used to elucidate fundamental molecular and cellular mechanisms. Research projects include understanding pathways that regulate the balance between cell survival and cell death, neuronal development, bacterial pathogenesis, cell growth and proliferation, and inflammation.

The Signaling and Molecular Pharmacology Program nucleates the campus-wide Cell Signaling San Diego Center, which unites researchers passionate about understanding the molecular mechanisms of cell signaling with the goal of leveraging this understanding to treat disease.

Program Director

 

Co-Directors

 

Program Faculty

Antal, Corina cantal@health.ucsd.edu
Brown, Joan Heller jhbrown@health.ucsd.edu
Brunton, Larry  LBrunton@health.ucsd.edu
Chang, Geoffrey g1chang@health.ucsd.edu
Daneman, Richard  rdaneman@health.ucsd.edu
Dennis, Edward A. edennis@ucsd.edu
Dorrestein, Pieter pdorrestein@health.ucsd.edu
Gonzalez, David djgonzalez@health.ucsd.edu
Guan, Kun-Liang kuguan@health.ucsd.edu
Gustafsson, Asa abgustafsson@health.ucsd.edu
Gutkind, J. Silvio sgutkind@health.ucsd.edu
Handel, Tracy thandel@health.ucsd.edu
Hunter, Tony  hunter@salk.edu
Hook, Vivian vhook@health.ucsd.edu
Idoyaga, Juliana jidoyaga@health.ucsd.edu
Insel, Paul pinsel@health.ucsd.edu
Joiner, William wjoiner@health.ucsd.edu
Karin,Michael mkarin@health.ucsd.edu
Leffert, Hyam hleffert@health.ucsd.edu
Mendiola, Andrew asmendiola@health.ucsd.edu
Miyamoto, Shigeki smiyamoto@health.ucsd.edu
Myers, Sam sam@lji.org
Newton, Alexandra anewton@health.ucsd.edu
Obara, Christopher cobara@health.ucsd.edu
Printz, Morton mprintz@health.ucsd.edu
Quehenberger, Oswald oquehenberger@health.ucsd.edu
Rangamani, Padmini prangamani@health.ucsd.edu
Rao, Anjana arao@lji.org
Saltiel, Alan asaltiel@health.ucsd.edu
Schöneberg, Johannes jschoeneberg@health.ucsd.edu
Sicklick, Jason  jsicklick@health.ucsd.edu
Sunahara, Roger rsunahara@health.ucsd.edu
Taylor, Susan staylor@ucsd.edu
Trejo, JoAnn jotrejo@health.ucsd.edu
Vallon, Volker vvallon@health.ucsd.edu
Yaksh, Tony tyaksh@health.ucsd.edu
Yang, Jing jingyang@health.ucsd.edu
Zhang, Jin jzhang32@health.ucsd.edu
Novel imaging techniques are used to visualize intracellular signaling in real time in live cells, and biochemical, molecular biological, cellular and biophysical approaches are used to elucidate fundamental molecular and cellular mechanisms.

Interested in research collaboration or training opportunities?


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